Anti-zona p. antibody

Importance in the clinical routine for: Gynaecologists to diagnose fertility disorders.

Autoantibodies in serum of female patients directed against antigens of the zona pellucida, antizona pellucida antibodies or zona pellucida antibodies, are crucial for female infertility. Pregnancy rates of women with antizona pelludica antibodies are drastically reduced even after an assisted reproduction therapy.

 

Around 30% of all infertility cases of unknown aetiology origin in an immunopathological response of the woman. Anti-sperm antibodies prevent spermatozoa migration into the female genital tract while autoantibodies against ovarial tissue or zona pellucida antigens inhibit egg maturation as well as the binding of or penetration by spermatozoa. At request we will be glad to send to you further information on relevant literature concerning anti-zona pellucida antibodies.

 

Anti-zona pellucida-antibody ELISA

Description:

This test is designed to quantify antibodies directed against zona pellucida (ZP) antigens. Application is recommended for all female patients showing fertility disorders of unknown aetiology or ovary malfunctions as well as in preparation for assisted reproduction therapy.

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Anti-zona pellucida-antibody ELISA - Ig-classifying (Ig-typing)

Description:

After detection of anti-zona pellucida antibodies, immunoglobulin classification of these antibodies (IgG, IgA, IgM) should be carried out since each class indicates a different immunological pathogenesis.

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Anti-zona pellucida antibody latex agglutination test

Description:

By means of the ZP-antibody latex agglutination test even smallest amounts of serum can be examined for the presence of zona pellucida antibodies.

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Anti-zona pellucida antibody haemagglutination test

Description:

With this test anti-zona pellucida antibodies possibly responsible for fertility disorders in the serum of subfertile women are diagnosed and the titer is determined.

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