Anti-ovary antibody

Importance in the clinical routine for: Gynecologists to diagnose fertility disorders

Around 30% of all infertility cases of unknown etiology originate in an immunopathological response of the female patient. Anti-sperm allo-antibodies prevent the migration of the spermatozoa through the female genital tract while autoantibodies against ovarian tissue (anti-ovary antibodies or ovary antibodies) or zona pellucida antigens (anti-zona pellucida antibodies or zona pellucida antibodies) inhibit egg maturation as well as the binding of or penetration by spermatozoa. Autoantibodies in serum of female patients directed against antigens of ovarian tissue, antiovary antibodies (ovary antibodies), may play a crucial role in female infertility and in the outcome of an assisted reproduction therapy.  Usually, the spermatozoa-oocyte-interaction and consequently the fertilization are impaired. Yet antiovary antibodies may also hinder egg maturation and may cause somatopathic disorders in women. Pregnancy rates of these patients with antiovary antibodies are drastically reduced even after an in-vitro fertilization therapy.

 

Anti-ovary antibody ELISA

Description:

Quantitative ELISA to determine antibodies directed against ovarian antigens.

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Anti-ovary antibody ELISA - Ig-classifying (Ig-typing)

Description:

After detection of anti-ovary antibodies, a classification of these immunoglobulins (IgG, IgA, IgM) may be carried out.

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Anti-ovary antibody latex agglutination test

Description:

By means of the ovary antibody latex agglutination test even smallest amounts of serum can be examined for the presence of anti-ovary antibodies.

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Anti-ovary antibody haemagglutination test

Description:

With this test anti-ovary antibodies possibly responsible for fertility disorders in the serum of subfertile women are diagnosed and the titer is determined.

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